The roster was selected internally by NetherRealm Studios with input from DC Comics. The main goal during the selection process, which took around three to four months, was to create a cast featuring a wide range of characters with regards to size, ability, and level of superpower. Characters were also chosen based on criteria such as gender, popularity, and how well they fit within the Injustice storyline. The addition of each playable hero and villain required about six weeks of development. The characters were designed with the intent to make each fighter unique. Fighting styles and movesets were tailored to the lore and personality of each character. Ed Boon stated that DC Comics had given NetherRealm a large amount of freedom with their properties, allowing them to put their own spin on characters. Several other characters from the DC Universe also appear as non-player characters, making cameo appearances in story cutscenes, stages, and other game modes.
Featuring a vast number of playing modes as well as bonus features, Injustice: Gods Among Us also includes a single-player campaign, which presents the events that occur after Superman destroys Metropolis. Being tricked by Joker, Superman devastates the city, killing innocent civilians along with his beloved Lois Lane; however, some of the world’s mightiest super heroes led by Batman manage to escape. Enraged and helped by a series of superheroes, Superman decides to introduce a new regime in Metropolis, but Batman and his rebels (insurgents) fight to stop him and free the remaining survivors.
The gameplay in Injustice: Gods Among Us is similar to the one experienced in Mortal Kombat 2011, which also developed by NetherRealm Studios, but there are several important changes that can be observed by players.
The Characters are split between two characteristics: Power and Gadget. For the most part, these categories mainly affect how the characters interact with the Arenas.
Power Characters are usually big and strong. They are the type of heroes and villains that are really "super," and got their powers through unusual ways. When they interact with arenas, they can throw cars, break statues, etc.
Gadget Characters are usually the heroes and villains that rely on tech and gadgets, or aren't as physically strong as the Power Characters. Normally, these characters don't have true super powers, just like Batman and Green Arrow. When they interact with Arenas, they may jump off obstacles or hit an enemy into an object.
List of playable characters:
- Aquaman (Arthur Curry)
- Ares (Olympian God of War)
- Bane (Antonio Dorrance)
- Batman (Bruce Wayne)
- Black Adam (Teh-Adam)
- Catwoman (Selina Kyle)
- Deathstroke (Slade Wilson)
- Doomsday (name unknown)
- The Flash (Barry Allen)
- Green Arrow (Oliver Quinn)
- Green Lantern (Hal Jordan)
- Harley Quinn (Harley Frances Quinzel)
- Hawkgirl (Shayera Hol)
- The Joker (name unknown)
- Killer Frost (Louise Lincoln)
- Lex Luthor (Alexander Luthor)
- Nightwing (Richard Grayson)
- Raven Roth
- Shazam (Billy Batson)
- Sinestro, Thaal
- Solomon Grundy (formery Cyrus Gold)
- Superman (Kal-El/Clark Kent)
- Wonder Woman (Princess Diana)
List of downloadable characters:
- Batgirl (Barbara Gordon)
- General Zod
- Lobo
- Martian Manhunter (J'onn J'onnz)