
When he left again with Killian, Hogan discretely followed and eventually tailed Savin to a public drop where he was delivering ampules to a fellow Extremis subject. Hogan interfered in an attempt to snatch evidence, and Savin stepped in to stop him. The altercation was interrupted when his contact's Extremis virus went critical and exploded the man. Savin's right foot was blown off in the explosion, and yet he was still able to get up and walk away, regrowing a new one as he left the scene.
On his next mission for Killian, Savin was deployed to the mansion of Tony Stark to kill the industrialist. Watching from the armed helicopter as Stark's home fell under a withering missile assault he could only report back that the house was destroyed with no body to be seen.
He encountered Stark soon enough however, when sent with Ellen Brandt to Rose Hill, Tennessee, to recover documents that could incriminate his benefactor. Instead they found Stark alive and well, and attempted to capture him. Brandt was killed, and Savin temporarily incapacitated, by Stark's improvised tactics.

Savin's next mission was to pilot the captured Iron Patriot battlesuit in a move against President Ellis of the United States. To that end he posed as Col. James Rhodes, the normal wearer of the Iron Patriot, and marched onto Air Force One along with the presidential contingent. Once the jet was well underway he overpowered the security team, captured the president and stuffed him into the suit to be delivered back to Killian.
After the president was well clear of the plane, Eric Savin planted a bomb and prepared to leave. He was interrupted by the arrival of Tony Stark in his guise of Iron Man, and the two fought. Savin surprised Stark with the extent of his Extremis abilities, but eventually Stark beat him when he activated the "unibeam" weapon in the Iron Man armor's chest. The weapon discharge blasted a gaping hole right through Savin's chest, killing him before his heart could regenerate.